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Atmospheric & Vacuum Drying Constant Weight Tester

One instrument covering both atmospheric-pressure and vacuum (reduced-pressure) loss on drying — replacing oven, vacuum oven, desiccator and balance, to constant weight within 0.3 mg.

DCT-81-ADCT-121-A

Purpose | What it does for you

Purpose-built for accurate, reliable moisture determination. Two modes: atmospheric-pressure heated loss on drying (replacing oven, cooling desiccator and balance) and vacuum/reduced-pressure loss on drying (replacing vacuum oven, desiccator and balance). For heat-sensitive, oxidation-prone samples or those with low-boiling components — certain APIs, herbal materials, foods and condiments — vacuum drying completes at a lower temperature, avoiding apparent weight loss from decomposition.

Key Features

  • Dual mode: atmospheric heated drying and vacuum constant-temperature drying
  • 0.3 mg constant weight with fully automated process control
  • Vacuum chamber, drying oven, cooling chamber and weighing chamber share one cabinet — small footprint
  • Balance protected against heat, moisture, corrosion and flame
  • Flame- and explosion-safe design with automatic over-temperature shutdown
  • Graphical full-process monitoring with multiple report formats; optional GMP Computerized System module

Operating Principle

Vacuum (reduced-pressure) temperature-controlled drying or atmospheric heated drying → cooling → constant-temperature weighing. Samples in dishes enter the temperature-controlled vacuum chamber and are dried at the set temperature and vacuum level, then cooled to the setpoint and weighed by the built-in analytical balance inside the same cabinet. The loop repeats automatically until the constant-weight difference is below 0.3 mg. A thermal shield isolates the balance from the vacuum chamber so heat convection and air currents cannot disturb readings.

This instrument is the only one of its kind in China and is already in service at drug-control institutes across multiple provinces and municipalities. If you would like to know more, please contact us directly.

Application Scenarios

  • Loss on drying of APIs and excipients (Chinese Pharmacopoeia Part IV)
  • Moisture in food by direct drying and vacuum drying (GB 5009.3)
  • Moisture and water content of herbal materials and decoction pieces
  • Moisture control in condiments, sugars and dehydrated vegetables
  • Moisture in the salt industry by loss-on-drying method (GB/T 13025)
  • Total solids determination and moisture method development

Compliance Standards

Chinese Pharmacopoeia Constant-Weight General Rules, Chinese Pharmacopoeia Vol.4 Loss-on-Drying Test, Chinese Pharmacopoeia Vol.4 Moisture Determination (oven-drying / vacuum-drying), Chinese Pharmacopoeia Vol.4total solids test, GB 5009.3 Food Moisture Determination(direct drying method/vacuum-drying method), GB/T 13025 general salt-industry moisture determination test method(loss-on-drying method)

Industries Served

  • Pharmaceutical & Biopharmaceutical
  • Food & Condiments
  • Traditional Chinese Medicine & Herbal
  • Third-Party & Government Testing Institutes
  • Public Health CDC & Customs Technical Centers
  • Material R&D, Universities & Institutes
  • Cosmetics & Personal Care

Frequently Asked Questions

When should I choose vacuum drying instead of atmospheric drying?

Choose vacuum drying when the sample is heat-sensitive (decomposes, discolours or melts at high temperature), oxidation-prone, or contains low-boiling solvents/volatiles. Lowering the pressure markedly reduces the boiling point of water so drying completes at a lower temperature, preventing non-water volatile loss from being counted as moisture.

Can the instrument handle very small sample masses?

Yes. Dishes are 75 mL standard and the actual sample mass follows your method; with a 0.3 mg constant-weight criterion and a 0.1 mg balance, results stay stable even at low sample masses. For ultra-micro samples, please confirm the approach with us first.

When should I use atmospheric drying versus vacuum drying?

It depends on how much heat the sample tolerates. Atmospheric mode performs heated loss on drying and moisture content, replacing the oven, desiccator and balance in one unit. Vacuum mode dries at low temperature inside an evacuable chamber — lowering the pressure lowers the boiling point of water, so moisture leaves at a lower temperature, which suits heat-sensitive and oxidation-prone samples that would otherwise decompose or oxidise. Both modes share the same constant-weight criterion (0.3 mg, at 0.1 mg balance resolution), so results are directly comparable.

Why is the constant-weight criterion set at 0.3 mg?

Pharmacopoeias and GB methods usually define constant weight as a difference of no more than 0.3 mg between two consecutive weighings (a few standards use 0.5 mg or 0.2 mg). The instrument judges at ≤0.3 mg by default, which covers most pharmacopoeia and food-contact methods; if your standard specifies another criterion, confirm applicability with an engineer before ordering.

Are evaporation residue, non-volatile matter and overall migration the same thing?

No. Overall migration is the total non-volatile substance transferred from a food-contact material under a specified simulant and contact condition; evaporation residue is the mass left after the soak or extract solution is taken to dryness; non-volatile matter refers specifically to the fraction that does not volatilise at that temperature. Their sample preparation and simulants differ, but all three end with evaporation, drying and constant-weight weighing, so one constant-weight tester serves them all.

Can loss on drying be reported directly as water content?

They are not equivalent. Loss on drying is everything the sample loses at the specified temperature — water, residual solvent and other volatile components; water content means H₂O specifically and is usually determined by Karl Fischer titration or a dedicated moisture analyser. The two figures approach each other only when water is the sole volatile present. A compliance report should state the method and conditions for each.

How do ignition residue, ash, acid-insoluble ash and loss on ignition differ?

The four differ in temperature, duration and preparation, but all end in the same high-temperature ignition, cooling and constant-weight weighing step, so one high-temperature instrument covers them. Ignition residue is the inorganic residue left after high-temperature ignition; ash is what remains after food, pharmaceutical or herbal material is ignited at a specified temperature; acid-insoluble ash treats the ash further with acid and keeps only the insoluble part, to reveal sand and other extraneous matter; loss on ignition (LOI) is the mass percentage lost by solid waste, building materials or minerals at high temperature.

Does LabStone support OEM/ODM and customised instruments?

Yes. Standard models ship as-is, while chamber count, specimen size, fixtures, temperature range and software modules (including the GMP Computerized System module) can be tailored to your SOP and URS. IQ/OQ/PQ validation documentation packages are available.

What is the typical lead time, and how is shipping handled?

Standard models usually ship in 4–8 weeks; customised builds depend on the agreed scope. Instruments are packed in export wooden cases and can move by sea, air or rail. We supply proforma invoice, packing list and certificate of origin (CO / Form E), and work under EXW, FOB, CIF or DAP terms.

How are installation, training and calibration handled after delivery?

We provide remote installation guidance, bilingual (Chinese/English) manuals and video training; on-site commissioning by our engineers is available. Users can self-calibrate with standard weights, reference films or calibrated leak standards, and third-party calibration certificates can be supplied.

What is the warranty, and how are spare parts supplied?

The instrument carries a 12-month warranty from acceptance plus lifetime maintenance support. Consumables (molecular sieve, desiccant, sealing grease, printer paper) are kept in long-term stock, and key components are international brands available worldwide. We respond to technical enquiries within 24 hours.

Do the instruments comply with ASTM, ISO and pharmacopoeia standards?

Yes. Every instrument lists its applicable standards on the specification page (ASTM, ISO, GB, YBB, Chinese Pharmacopoeia, USP, EP, JIS, DIN, TAPPI and more). The software outputs raw records and reports suitable for audit trails, with an optional GMP / FDA 21 CFR Part 11 compliance module.

Which languages does the software support, and can it integrate with a LIMS?

The software ships with Chinese and English interfaces; other languages can be added on request. Data export is available over RS232, USB, Ethernet or Wi-Fi, and reports can be exported to Excel, PDF or structured files for LIMS integration.